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A nerve cell or neuron consists in a cell body (“soma”) from which emerge threadlike extensions or processes called dendrites and axons, which are long, slender projections of the neuron, or processes that conduct electrical impulses away from the neuron's soma. Axons can reach up to 1 meter in length.

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Document 3569 - ID:5dc083f68f61f

ELISA was used to determine cytokine production. Cell surface marker expression was assessed by flow cytometry. LBH589 was administered in vivo by IP injections. Results: In vitro, LBH589 treatment decreased the proliferation of both human and murine melanoma cells, inducing a cell cycle arrest in G1.

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